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Join AstraZeneca Oncology DMPK and help turn science into life-changing medicines for patients. About AstraZeneca AstraZeneca is a global biopharmaceutical company united by a bold ambition: to redefine cancer and restore patients' lives. Oncology R&D is a major growth engine, with a diverse pipeline across all stages of development. We collaborate across disciplines to solve complex problems and bring the next generation of cancer therapies to patients. About The Site Our Waltham campus is a modern, collaborative environment with cutting-edge technology and more than 800 scientists and professionals. It is a short drive from Boston and designed to foster teamwork and cross functional science. As part of our commitment to patients and scientific excellence, we plan to relocate to Kendall Square/Cambridge in 2026, expanding our access to the world class biotech ecosystem. Business Area AstraZeneca Oncology is one of the fastest growing teams in the industry. 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What you will do Independently develop and validate bioanalytical methods, analyze biological samples using quantitative LC-MS/MS assays, analyse and present findings back to project teams. Lead quality control and data review for BA to ensure accuracy, reproducibility, and regulatory readiness where applicable. Conduct operation, maintenance, and troubleshooting of key platforms: laboratory automation/liquid handling, mass spectrometers and LC equipment such as Hamilton liquid handling system, AB Sciex triple quadrupoles, HRMS and Shimadzu LC Develop and implement state-of-the-art technologies in the field of drug metabolism. Support the department's leadership team in both the strategic vision for the department and in the efficient and progressive running of the department. Ensure compliance with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations. Essential Requirements BS/MS (or equivalent) in pharmaceutical sciences, chemistry, biochemistry, or related discipline, with 4+ years of industry experience. A solid foundation in bioanalytical chemistry, with demonstrated expertise in LC\u2011MS/MS, including method development and quantitative analysis. Hands-on experience with the operating, maintaining, and troubleshooting mass spectrometers and LC equipment; familiarity with laboratory automation/liquid handling and experience evaluating and implementing new bioanalytical technologies. Experience conducting in vitro mechanistic studies to address ADME-related challenges is a plus. Excellent problem-solving, organization, documentation, and communication skills; ability to thrive in a collaborative, multidisciplinary, fast\u2011paced environment. Why AstraZeneca? At AstraZeneca, you're empowered to push the boundaries of science in an inclusive culture that champions diversity, collaboration, and lifelong learning. 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